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Experts from Brigham Young University in Utah discovered that addiction comes from an 'overcorrection' within the brain, a PsychCentral report said.

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The U.S. Food and Drug Administration has approved the application of Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) to help manage chronic obesity in adults with a body mass index (BMI) of greater than 27, provided they also are afflicted by weight-related health problems such as Tupe2 diabestes, high-cholesterol and/or hypertension (hypertension).Contrave is a combination of two FDA-approved drugs, naltrexone and bupropion, in the extended-release formulation. Naltrexone is eligible to treat alcohol and opioid dependence. Bupropion is eligible to treat depression and seasonal affective disorder in addition to being an aid to quitting smoking treatment.'Obesity continues to be a major public health concern,' said Jean-Marc Guettier, M.D., director from the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination with a healthy lifestyle that features a reduced-calorie exercise and dieting, Contrave provides another treatment selection for chronic weight management for people who are obese or are overweight and also have at least one weight-related health issue.'The drug's effectiveness was evaluated in multiple many studies that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated first year. All patients received lifestyle modification that consisted of a reduced- calorie diet and regular physical activity. Results from a medical trial that enrolled patients without diabetes showed that patients had the average weight loss of 4.1% as opposed to participants who have been given placebos) throughout a 12- month period, while another study involving patients with diabetes type 2 symptoms had a typical weight loss of 2% over treatment with placebo at 12 months.

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Seizures really are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise blood pressure and heart rate, and mustn't be used in people with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

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--Participating in support groups that help the family with the addict recover (such as Al-Anon or Nar-Anon).

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Researchers discovered that participants taking this drug for any year, lost excess weight within four weeks and have kept the extra weight off during the entire 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, which may make them more potent and safer.

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'The intent on this bill would be to give police force and district attorneys something to address illicit drug use among expecting mothers through treatment programs," Tennessee governor Bill Haslam said.

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