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The FDA announced the approval of the new weight loss drug on Sept. 11, 2014. The drug name is Contrave.

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Researchers found out that participants investing in this drug for a year, dropped excess weight within one month and have kept the load off during the entire 56 weeks with the study. Contrave can be a combination with the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them far better and safer.

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Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug may also raise hypertension and heart rate, and really should not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

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The U.S. Food and Drug Administration has approved the application of Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) to help you manage chronic obesity in older adults with a body mass index (BMI) of greater than 27, so long as they also suffer from weight-related health problems such as Tupe2 diabestes, high cholesterol levels and/or hypertension (high blood pressure).Contrave can be a combination of two FDA-approved drugs, naltrexone and bupropion, in a extended-release formulation. Naltrexone is eligible to treat alcohol and opioid dependence. Bupropion qualifies to treat depression and seasonal affective disorder and as an aid to stopping smoking treatment.'Obesity continues to be a major public health concern,' said Jean-Marc Guettier, M.D., director with the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination with a healthy lifestyle which includes a reduced-calorie diet and exercise, Contrave provides another treatment selection for chronic weight management for people who are obese or are overweight and possess at least one weight-related health condition.'The drug's effectiveness was evaluated in multiple clinical trials that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated for starters year. All patients received lifestyle modification that contains a reduced- calorie diet and regular exercise. Results from a clinical trial that enrolled patients without diabetes indicated that patients had a normal weight loss of 4.1% as opposed to participants who were given placebos) after a 12- month period, while a separate study involving patients with diabetes type 2 had an average weight loss of 2% over treatment with placebo at 12 months.

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