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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to lose weight naturally can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you should err on the side of caution and allow the FDA do its job and demand some study be done so your public recognizes the side effects and dangers of the medications before we take them. Keep in mind that drug companies are in business to generate income and that they would say almost anything to keep people on the medications.

Researchers discovered that participants investing in this drug for a year, lost excess weight within a month and have kept the body weight off through the entire 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more potent and safer.

Combo-pilling may be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is now popular will be the fact that as of right now there are not any long term prescription slimming capsules that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug could also raise blood pressure and heartrate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients towards the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.