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Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err along the side of caution and permit the FDA do its job and demand some investigation be done so your public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants taking this drug to get a year, lost weight within four weeks and have kept the body weight off through the entire 56 weeks of the study. Contrave can be a combination with the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which may make them far better and safer.

Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular will be the fact that at the time of right now there are not any long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise blood pressure levels and heart rate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.

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