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Researchers found out that participants taking this drug to get a year, lost weight within four weeks and have kept the extra weight off throughout the 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which might make them more effective and safer.

Combo-pilling may be the newest fad or better yet the newest into the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that by right now there are not any long term prescription diet pills that have been authorized by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and must not be taken in those with seizure disorders. The drug may also raise blood pressure levels and heartbeat, and mustn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not used in patients with uncontrolled high blood pressure levels, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

Most of the combinations which can be used to enhance weight-loss involve an amphetamine with an antidepressant. Phentermine and Prozac certainly are a popular combination that have been around for quite a while, and even though it has been around nobody wants to truly combine the 2 and try to get FDA approval to advertise it as a weight loss pill. Right there should raise some warning flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something have to be wrong while using combination. In fairness there is one weight loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and drug addiction, using the antidepressant bupropion (Wellbutrin, Zyban) many experts have given the just do it to move forward by an FDA advisory committee, but at the time of yet will not be approved.

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