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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight loss in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to lose weight naturally can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you need to err on the side of caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies come in business to earn money and that they would say anything to keep people on their medications.

    Researchers found that participants taking this drug to get a year, dropped a few pounds within one month and have kept the load off throughout the 56 weeks of the study. Contrave is often a combination in the drugs naltrexone and bupropion, which appears to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, which may make them far better and safer.

    Combo-pilling may be the newest fad or in addition to this the newest ahead under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that since right now there are no long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and shouldn't be taken in those with seizure disorders. The drug can also raise hypertension and pulse rate, and shouldn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise hypertension and heartbeat and must stop used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

    "This is the first drug I'm alert to that targets both the appetite and reward centres inside brain," he explained.

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