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The Food and Drug Administration, FDA, has approved the drug Vivitrol for the treatment of opioid dependence in accordance with a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight-loss and the those who go through it you ought to err to the side of caution and allow the FDA do its job and demand some study be done so the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies have been in business to generate income and that they would say everything to keep people on their own medications.

Researchers found that participants using this drug for the year, lost weight within 4 weeks and have kept the body weight off through the 56 weeks of the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more effective and safer.

Combo-pilling is the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that at the time of right now there are not any long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in people with seizure disorders. The drug also can raise blood pressure level and heart rate, and must not be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must not used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

Suboxone is made up of two drugs; buprenorphine and naloxone. The naloxone is irrelevant if the addict uses the medication properly, but if the tablet is dissolved in water and injected the naloxone can cause instant withdrawal. When suboxone is utilized correctly, the naloxone is destroyed within the liver right after uptake in the intestines and has no therapeutic effect. Buprenorphine could be the active substance; it is absorbed beneath the tongue (and through the mouth) but destroyed with the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I have used this formulation if the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I have treated addicts who've had gastric bypass, in which the first section of the intestine is bypassed and the stomach contents empty in a more distal area of the small intestine. In such cases the naloxone escapes ?first pass metabolism', the process with normal anatomy the place that the drug is taken up through the duodenum and transferred straight to the liver from the portal vein, where it is quickly and completely destroyed. After gastric bypass naloxone can be taken up by areas of the intestine which aren't served by the portal system, causing blood degrees of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.