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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight loss in addition to a reduced-calorie diet and exercising.

Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err along the side of caution and let the FDA do its job and demand some research be done so the public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on the medications.

Researchers found out that participants using this drug for a year, dropped excess weight within one month and have kept the extra weight off during the entire 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which can make them more effective and safer.

Combo-pilling may be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular is the fact that at the time of right now there are no long term prescription weightloss pills that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and must not be taken in people with seizure disorders. The drug can also raise hypertension and pulse rate, and must not be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high blood pressure, in addition to by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.

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