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It was discovered that naltrexone and bupropion combined, which may be marketed later on as Contrave, provide better weight loss results than diet and exercise alone.
Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it you ought to err on the side of caution and permit the FDA do its job and demand some investigation be done so your public knows the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say anything to keep people on their medications.
Researchers found out that participants taking this drug to get a year, dropped excess weight within one month and have kept the extra weight off during the entire 56 weeks of the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more potent and safer.
Combo-pilling could be the newest fad or even better the newest ahead under scrutiny and so it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that since right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be licensed by the FDA.
Seizures certainly are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure levels and heart rate, and mustn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high blood pressure level, along with by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking.
"There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.