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On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians that are struggling with alcoholism may benefit especially from naltrexone, among three medications licensed by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that creates them planning to benefit from naltrexone, in comparison with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are available online ( in the journal Neuropsychopharmacology and will also be published in an upcoming print edition of the journal.

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Researchers discovered that participants investing in this drug for the year, dropped a few pounds within a month and have kept the body weight off through the entire 56 weeks of the study. Contrave is a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of several active ingredient, which can make them far better and safer.

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Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise blood pressure and pulse rate, and must not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

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Other people who should avoid using Contrave are patients suffering from bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave mustn't be prescribed for women who are pregnant or looking to become pregnant.

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The Promises Treatment Centers, estimates that between five and 10 percent of the patients at his doctors are given naltrexone. Those more than likely to receive it are individuals with a history of early relapse—those who have been treated before and still have not had the opportunity to maintain sobriety for much more than 30 days.

Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you ought to err on the side of caution and allow the FDA do its job and demand some investigation be done so your public recognizes the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on the medications.

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Seizures can be a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure and heartrate, and really should not be used in people with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

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"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.