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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence according to a news release by them on 10-12-2010.

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Researchers discovered that participants investing in this drug for a year, lost excess weight within a month and have kept the body weight off through the entire 56 weeks of the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more potent and safer.

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Seizures can be a side effect with Contrave and must not be taken in people with seizure disorders. The drug could also raise blood pressure and heartrate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients towards the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.

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Experts from Brigham Young University in Utah found that addiction is a result of an 'overcorrection' in the brain, a PsychCentral report said.

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Seizures are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise blood pressure levels and heartrate, and shouldn't be used in people who have a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise hypertension and heartbeat and must stop used in patients with uncontrolled high hypertension, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

"There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.

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The Promises Treatment Centers, estimates that between five and ten percent of the patients at his doctors are helped by naltrexone. Those most likely to receive it are individuals with a history of early relapse—individuals who have been treated before and still have not had the opportunity to maintain sobriety for considerably more than four weeks.

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After a patient will be admitted inside a rehab centre for that treatment of opiate detoxification, medical practitioner immediately start detoxifying the patients body. The patient would feel pain if the treatment starts when she or he are in full senses, so usually an anesthesia injection will be injected of their body to make them drift off. After the patient had opted into deep sleep as a result of affect of the injection opium blockade is being used for narcotics medication. These opium blockade injections might be best of it is kind for narcotics medication since they are very helpful in eradication of symptoms like anti-nausea and muscle calmness. These are intravenous injections that help in curing the patients through the harmful toxins effects. For a speedy recovery and medication of opiate detoxification, opium blockade injections like nalaxone, naltrexone etc are utilized which makes a quick detoxification from narcotics and also the patient has been discharged through the rehab after full two days of treatment.

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