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  • The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and physical activity.

    Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err to the side of caution and permit the FDA do its job and demand some investigation be done so that the public is aware of the side effects and risks of the medications before we take them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on their medications.

    Researchers found that participants taking this drug for any year, dropped excess weight within 4 weeks and have kept the extra weight off through the entire 56 weeks in the study. Contrave is really a combination in the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of several active ingredient, which might make them more effective and safer.

    Combo-pilling will be the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular will be the fact that as of right now there are not any long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be authorized by the FDA.

    Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug may also raise hypertension and heartrate, and really should not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure, in addition to by you are not heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation.

    Most of the combinations which can be used to enhance weight loss involve an amphetamine plus an antidepressant. Phentermine and Prozac certainly are a popular combination which have been around for a long time, although it has been around no one wants to truly combine both the and try to get FDA approval to promote it as a fat loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something have to be wrong while using combination. In fairness there is certainly one weight reduction combination pill that is in front of the FDA now Contrave?which couples naltrexone, employed to treat alcohol and substance abuse, while using antidepressant bupropion (Wellbutrin, Zyban) it is often given the just do it to move forward by an FDA advisory committee, but as of yet will not be approved.

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