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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight loss in addition to a reduced-calorie diet and exercise.

Using two separate drugs to shed weight can be very effective you can find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err assisting caution and let the FDA do its job and demand some study be done so the public knows the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on their medications.

Researchers found out that participants using this drug to get a year, lost weight within one month and have kept the body weight off throughout the 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them more potent and safer.

Combo-pilling is the newest fad or in addition to this the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that by right now there are not any long term prescription weightloss pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise hypertension and heart rate, and really should not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high hypertension, along with by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

New UCLA study on smokers with mental, drug, and alcohol problems