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Evidence is increasing that addiction without exception is related to difficulty with the brain's reward center, specially the mesolimbic system. This part of the problem regulates reward responses in establishing food and sex, plus nurturing infants and children. One of the most important neurotransmitters involved in reward responses, both once they malfunction and once they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the amount of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to lose weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it you need to err assisting caution and let the FDA do its job and demand some study be done so that the public is aware of the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on the medications.

Researchers discovered that participants investing in this drug for the year, dropped a few pounds within four weeks and have kept the load off through the entire 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which might make them more effective and safer.

Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that since right now there are no long term prescription weight loss supplements that have been approved by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure and pulse rate, and must not be used in those with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high hypertension, in addition to by a person with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.

To keep up with essentially the most current articles from Wendi, the Indiana Addiction Recovery Examiner, click the subscribe link near the top of the page to receive email notification when new content is published. Please leave a comment for just about any article.