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On September 26, UCLA researcher reported the outcomes of a study, which indicated that Asians who're struggling with alcoholism may benefit especially from naltrexone, considered one of three medications licensed by the U.S. Food and Drug Administration (FDA) to the treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that creates them likely to benefit from naltrexone, in contrast to about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are presently available online ( inside journal Neuropsychopharmacology and are published in a upcoming print edition of the journal.
Using two separate drugs to lose weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err on the side of caution and let the FDA do its job and demand some study be done so your public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies are in business to earn money and that they would say anything to keep people on his or her medications.
Researchers found that participants using this drug for a year, lost excess weight within 4 weeks and have kept the load off throughout the 56 weeks from the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, which might make them more potent and safer.
Combo-pilling is the newest fad or also the newest to come under scrutiny and so it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that at the time of right now there aren't any long term prescription slimming capsules that have been authorized by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.
Seizures are a side effect with Contrave and really should not be taken in individuals with seizure disorders. The drug may also raise blood pressure level and heart rate, and really should not be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise blood pressure level and heartrate and must not be used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.
"There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.